Posts Tagged ‘Depression’

Antidepressants Increase Risk of Suicidal Behavior in Children and Young Adults, Don’t Reduce Risk in Adults, Study Says

Monday, August 28th, 2023

Other recent research has found antidepressants double the risk of suicidal thoughts and actions in adults.

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, August 17, 2023 — A new study adds fresh evidence that treatment for depression with antidepressants increases the risk of suicidal behavior, including attempted and completed suicides, in children and young adults under age 25. The findings support previous studies that have also found a greater risk of suicidal thoughts and actions in young people taking antidepressants – drugs that are prescribed to reduce that risk.

“The present study finds similar results to prior observational research – that is, consistent evidence of an increased risk of suicidality during treatment with SSRIs in children and adolescents,” wrote lead author Tyra Lagerberg, at the Karolinska Institutet in Stockholm, Sweden, and the psychiatry department at Oxford University’s Warneford Hospital in the U.K. The study was published in Neuropsychopharmacology.

Lagerberg led a team of Swedish researchers who used medical and death registry records of roughly 162,000 depressed individuals from 2006-2018 to find the risk of suicidal behavior within 12 weeks after the patients either were or were not started on selective-serotonin reuptake inhibitor (SSRI) antidepressants following a diagnosis of depression. Overall, the study revealed an increased risk of suicidal behavior among the antidepressant users.

The greatest increase in risk was to youth 6 to 17 years of age, who were three times more likely to engage in suicidal behavior, followed by 18- to 24-year-olds, whose risk was doubled.

“Our results confirm that children and adolescents under age 25 are a high-risk group, in particular children aged under 18 years,” Lagerberg concluded.

While this study did not find an increased risk of suicidal behavior from antidepressants in older patients or patients who previously attempted suicide, it did find that taking the drugs did not reduce the risk for these groups.

The research confirms the validity of the stringent, black-box warning first required in 2004 by the U.S. Food and Drug Administration (FDA) on antidepressant packaging to alert consumers and prescribers to the increased risk of suicidal thoughts and actions for children and adolescents. The action came after drug trials indicated that youth taking antidepressants were almost twice as likely to have suicidal thoughts or suicide attempts as those receiving placebos. The warning was expanded in 2007 to include young adults through age 24.

Critics have since complained that the warning resulted in more suicides by youngsters not treated with antidepressants. However, researchers recently re-analyzed clinical trial data and concluded that the data demonstrated an increased risk of attempted and completed suicides among youth taking antidepressants and that the FDA’s warning is clearly justified.

Other recent research has found antidepressants double the risk of suicidal thoughts and actions in adults. A re-analysis of safety summaries submitted to the FDA for approval of antidepressants found that the rate of suicide attempts in drug trials was about 2.5 times higher in adults taking antidepressants as compared to those given placebos.

Another study found that when healthy adults with no signs of depression were given antidepressants, their risk of suicidality and violence doubled.

Antidepressants may be prescribed to prevent suicides, but a recent examination of coroner inquests in which the decedents used antidepressants revealed that about half of the deaths were determined to be suicides. One in eight of the deaths involved an overdose of antidepressants.

More fundamentally, a landmark 2022 study questioned the prescribing of antidepressants at all, after finding the common reason for taking them – to correct a chemical imbalance in the brain – had no scientific basis. The study investigated whether evidence supported the theory that a low level of the brain chemical serotonin causes depression.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” the researchers wrote. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs. CCHR supports safe and science-based non-drug approaches to mental health.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office

No Clear Benefit, But Serious Side Effects Common for Older People Taking Antidepressants, Study Finds

Monday, August 21st, 2023

Adverse effects from taking antidepressants are more common and serious for the elderly because they have more fragile health and take more medications.

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, August 9, 2023 — A new review of recent medical literature on antidepressant use by older people with depression revealed no clear evidence of benefit, while adverse effects were found to be especially common and problematic. Alternative treatments for depression were advised.

The review was conducted to provide an overview of studies from the past decade of the benefit and harms of treatment of older persons with selective serotonin reuptake inhibitor (SSRI) antidepressants. The studies under review comprised depressed patients aged 55 and older who were taking SSRI antidepressants in comparison to control groups receiving placebos.

As reported in Mental Health Science, the evidence indicated that antidepressants have little, if any, benefit over placebos in this age group. There was even less evidence of depression remission.

“The evidence of the benefits of antidepressants in the elderly was weak and alternative treatments are advised,” wrote study author Michael Hvidberg, Ph.D., of the psychology department at the University of York in the U.K.

In the U.S., 15.6 million Americans aged 60 and older are prescribed antidepressants –
that’s one of every five (19%), with one in four (24%) of them women.

Adverse effects from taking the drugs are common and more serious among the elderly because they have more fragile health, deal with more medical issues, and take more medications. “Treatment with antidepressants may lead to more [adverse events] due to polypharmacy and age-related physiological changes,” Hvidberg writes, advising other treatment instead of the drugs.

Side effects of taking antidepressants include weight gain, nausea, insomnia, agitation, emotional blunting, sexual dysfunction, and even deepening depression. Psychiatrist Peter Breggin, M.D., describes antidepressants as neurotoxic because they harm and disrupt the functions of the brain and can cause abnormal thinking and behaviors, including anxiety, aggressiveness, loss of judgment, impulsivity, and mania, which can lead to violence and suicide.

Discontinuing antidepressants can bring on withdrawal symptoms, including electric shock-like sensations (“brain zaps” and “body zaps”), muscle spasms and tremors, hallucinations, confusion, irritability, and mania. One study found that more than half (56%) of people attempting to come off antidepressants experience withdrawal symptoms, with nearly half (46%) of them describing those symptoms as severe.

The new study’s finding of no clear benefit to patients from antidepressants is consistent with the results of a 2022 study, which found no clinically significant difference in measures of depression symptoms between adults treated with antidepressants and those taking placebos, whether over a shorter or longer time frame and regardless of the depression severity of the study participants.

Because the drugs have no strong evidence of benefit to patients, but carry the risks of significant side effects, researchers in another recent study advised primary care physicians not to prescribe antidepressants to depressed patients initially, but instead to recommend alternative approaches for treatment.  Similar guidance was issued in 2021 by the London-based National Institute for Health and Care Excellence, the organization that develops standards for health care practices in England.

One alternative approach to depression that has been repeatedly validated as effective in research studies is exercise. The results of one new study found that even exercise below levels of physical activity commonly recommended in health guidelines resulted in significant antidepressant benefits for older adults.

More fundamentally, a landmark 2022 study questioned the prescribing of antidepressants at all, after finding the common reason for taking them – to correct a chemical imbalance in the brain – had no scientific basis.  The study investigated whether evidence supported the theory that a low level of the brain chemical serotonin causes depression.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” the researchers wrote. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office

Half of Depressed, Anxious Teens Recover Without Mental Health Treatment, Study Finds

Monday, August 7th, 2023

Research indicates the resilience of adolescents is effective and can avoid the ineffectiveness, harms and costs of pharmacological and psychological treatments.

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, July 26, 2023 — A systematic review and meta-analysis on adolescents experiencing depression and/or anxiety reveals that half of them recovered on their own, without any mental health treatment.  Researchers say the result indicates that strengthening young people’s own resilience is key to their long-term mental health.

Noting that experiencing mental distress is common in the transition from adolescence to adulthood, a team of researchers reviewed previous studies to find the recovery rate of depressed and/or anxious adolescents who dealt with their teen angst without psychiatric drugs, psychotherapy, or other specific mental health treatment.  They found that within one year, half of depressed and/or anxious teens had recovered on their own.

“The findings suggest that after 1 year, about 54% of young people with symptoms of anxiety and/or depression recover without any specific mental health treatment,” according to the study’s lead author, Anna Roach, a PhD candidate at Queen Mary University of London.  Due to certain limitations of the study, the researchers suggest that the true rate of recovery is likely even higher. 

This result is an indication of teens’ ability to adapt and adjust to difficulties in life, “a sign of resilience, with young people bouncing back from their experience of distress,” the researchers wrote, reporting in the online peer-reviewed British medical journal, BMJ Open.

The high rate of recovery without involvement in the mental health system challenges the growing number of programs set up to screen and refer depressed or anxious teens to mental health practitioners for further evaluation and treatment.  As the researchers put it, “the question arises as to whether [teenagers] should routinely be considered for specialised treatments or whether one should wait with such decisions for a year, by which time about 54% are likely to have recovered without treatment.”

Instead of channeling young people into the mental health system, the study calls for new approaches to mental health care, noting also that psychiatric drugs and psychotherapy are both largely ineffective and costly.

Research on safe and effective alternative mental health treatment already exists.  For example, a 2023 study found that exercise is as effective in reducing symptoms of depression as antidepressant drugs or psychotherapy, regardless of the type or intensity of the exercise or whether done in a group or not.  Similarly, a 2020 study found exercise is effective in significantly reducing the symptoms of anxiety.

Many young people already avoid mental health treatment.  A recent study found that one in three depressed young adults preferred self-reliance instead of getting mental health treatment.  One in four cited concerns about being involuntarily committed to a psychiatric facility or having to take psychiatric drugs, while one in seven did not think mental health treatment would help them.

The most widely prescribed psychiatric drugs in the U.S. are antidepressants.  A recent study, published in World Psychiatry, advises doctors not to prescribe antidepressants as first-line treatment for most depressed patients because the benefit of the drugs is so small that it may not be clinically significant, and the drugs carry the risk of significant side effects.  Instead, the researchers suggest prescribing non-drug approaches first for the patients.

Some 45 million Americans are currently taking one or more antidepressants, including 5.7 million children and young adults under the age of 25, for whom the FDA requires a warning on the drug’s prescribing information of the increased risk of suicidal thoughts and actions.

Other adverse effects of antidepressants include weight gain, nausea, insomnia, agitation, emotional blunting and sexual dysfunction.  One recent study found that half of antidepressant users experience sexual problems, which can strain their relationships and lead to a worsening of their depression.   

Doctors have no clear guidance for tapering or discontinuing antidepressants, leaving their patients at greater risk of experiencing withdrawal symptoms that for many will be severe and incapacitating. 

A recent study found that more than 56% of people who attempt to come off antidepressants experience withdrawal effects, with nearly half (46%) of them rating the symptoms as ‘severe.’”

More fundamentally, a landmark 2022 study questioned the prescribing of antidepressants at all, after finding the common reason for taking them – to correct a chemical imbalance in the brain – had no scientific basis.

“These studies all point to the desperate need for a drastic overhaul of the badly broken U.S. mental health system, which relies on the psychiatric drugs and practices that scientific research has found ineffective and harmful,” says Anne Goedeke, president of the National Affairs Office of the Citizens Commission on Human Rights.

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

CCHR recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression, anxiety, or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health.  CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level.  The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office

New Study Finds Troubling Mental and Physical Side Effects Are Main Reason Patients Stop Taking Antidepressants

Monday, July 31st, 2023

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, July 19, 2023 — A new study investigating why patients stop taking antidepressants found the most common reason given was the adverse physical and mental side effects experienced. The findings add to prior research revealing the troubling, and even dangerous side effects of these mind-altering psychotropic drugs.

Researchers in the U.S. and U.K. analyzed 667 reviews posted on the online health forum WebMD by users of seven common selective serotonin reuptake inhibitor (SSRI) antidepressants. The most common reason users gave for discontinuing antidepressants was the negative side effects they experienced.

Mental side effects were the adverse events most mentioned in the reviews, including apathy, anxiety, insomnia, loss of sexual drive, and suicidal ideation. These side effects were reported more often in the online posts than in the formal reporting systems set up by the U.S. Food and Drug Administration and the U.K. Medicines and Healthcare Products Regulatory Agency, leading the researchers to note that the online comments provide valuable, additional information for government drug regulatory agencies about the adverse effects of SSRIs.

“It is not merely feasible to collect data from online comments and reviews regarding SSRI medication changes, but…doing so can provide important supplementary information to reporting systems,” wrote lead author Su Golder, PhD, of the University of York in the U.K., reporting in JAMA Network Open.

Other top adverse events reported by SSRI users as reasons for discontinuing antidepressants were physical side effects, such as dizziness, drowsiness, headache, diarrhea, vomiting, weight gain, itchiness, excessive sweating, and sexual dysfunction.

“These results suggest that reasons for changes in SSRI use can be identified in online drug reviews and that adverse events mentioned may reflect those more salient to patients for discontinuing their medication,” according to Golder.

Though the study was intended to discover why SSRI users discontinue antidepressants so that ways to keep them on the drugs could be developed, the study provides additional evidence of the harm from the drugs that users contend with. Other recent research findings on the negative effects of antidepressants are much more disturbing.

A 2019 study indicated that the rate of attempted suicide was about 2.5 times higher in those taking antidepressants as compared to placebo. Those results were similar to a 2016 study that found antidepressants, given to healthy adult volunteers with no signs of depression, doubled their risk of suicidality and violence.

Antidepressant use has risen significantly over the past 15 years – and so have suicides and senseless acts of violence like mass shootings. In 2020, some 45 million Americans, or roughly one in seven, were taking antidepressants, up from 34 million in 2006. This 32% increase in users parallels the 35% increase in suicides in the U.S. over the same period. During the same time, many school shootings and other acts of senseless violence were committed by individuals taking antidepressants or in withdrawal from them.

A 2020 study found that half of antidepressant users experience sexual problems that can strain their relationships and lead to a worsening of their depression.  In a 2017 survey of antidepressant users, 44% of respondents reported the drugs negatively impacted their sex lives, 27% their ability to work or study, and 21% their relationships with friends or family.

For all the risk of serious side effects, recent research has found little, if any, benefit to antidepressants over placebos.  A 2022 study found no clinically significant difference in measures of depression symptoms between adults treated with antidepressants and those taking placebos, whether over a shorter or longer time frame and regardless of the depression severity of the study participants.

Another study in 2018 found that those who used antidepressants any time during the 30-year period of the study had an 81% greater chance of having more severe depression symptoms at the end of that time.

More fundamentally, a landmark 2022 study questioned the prescribing of antidepressants at all, after finding the common reason for taking them – to correct a supposed chemical imbalance in the brain – had no scientific basis. The study investigated whether evidence supported the theory that a low level of the brain chemical serotonin causes depression.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” the researchers wrote. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office

Psychiatrists at Annual Conference Warned That Antidepressants They Prescribe Can Deaden Patients’ Emotions

Monday, June 26th, 2023

New study confirms patients’ common complaints of antidepressants deadening their emotions and harming their sex life.

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, June 15, 2023 — A new study presented at the annual conference of the American Psychiatric Association informed psychiatrists that the emotional blunting caused by the antidepressants they prescribe is a significant and under-recognized side effect patients may suffer.

The current study reviewed 25 prior studies related to the problem of antidepressant-induced emotional blunting, described as “a persistent diminution in both positive and negative feelings,” which the patients differentiated as side effects of the drugs rather than symptoms of their depression.

The researchers concluded that “emotional blunting was a significant patient-reported concern with antidepressants.” That dulling of emotions could also be experienced as a change in personality or as not feeling like oneself.

A separate study earlier this year also found that participants given a selective serotonin reuptake inhibitor (SSRI) antidepressant experienced a reduction in positive emotions, along with a significant increase in sexual problems that the researchers suggested could be due to the reduced emotional pleasure.

Sexual dysfunction is reportedly experienced by many patients on antidepressants. Half of the antidepressant users who responded to a recent survey reported experiencing sexual problems they did not have before taking the drugs – problems that can strain relationships and lead to a worsening of the depression for which the drugs are being prescribed.

These findings add new credibility to patients’ common complaints of antidepressants deadening their emotions and sex life.

Worse still, the sexual disability can persist indefinitely, even after antidepressants are discontinued.  The condition, referred to as post-SSRI sexual dysfunction, has no definitive treatment, a fact many patients were not made aware of by their prescribers before starting antidepressants.

A key rationale for prescribing antidepressants in the first place – to fix a chemical balance in the brain – was recently found to be without scientific merit. Researchers conducted a comprehensive review of the research that had looked into whether a lack of the brain chemical serotonin causes depression and concluded there was no convincing evidence to support the theory.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” wrote the study’s lead author, Joanne Moncrieff. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

Also challenging the prescribing of antidepressants are the results of a study which found that taking antidepressants led to worse depression symptoms for patients years later. Patients who used antidepressants at any time during the 30-year period of the study had an 81% greater chance of experiencing more severe depression symptoms at the end of the period.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and emotional symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuses and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office
202-349-9267

Primary Care Doctors Advised Not to Prescribe Antidepressants to Patients on First Visit for Mild to Moderate Depression

Monday, June 5th, 2023

NEWS PROVIDED BY

Citizens Commission on Human Rights, National Affairs Office

WASHINGTON, DC, May 25, 2023 — Researchers are advising primary care doctors not to prescribe antidepressants to patients with mild to moderate depression on their first visit because of the drugs’ limited effectiveness and risks of significant side effects. Their conclusion, based on reviews of the available evidence on antidepressants, was published in World Psychiatry, the journal of the World Psychiatric Association.

Noting that most depressed patients in primary care settings have mild to moderate depression, the researchers cite recent research that found the benefit of antidepressants for such patients is so small that it may not be clinically significant. Instead, the researchers suggest non-drug approaches for these patients.

“Antidepressants should not be prescribed at the first visit if the patient has mild to moderate depression, because they have a limited efficacy and may have significant side effects,” according to lead author Bruce Arroll, professor in the Department of General Practice and Primary Health Care at the University of Auckland in New Zealand.

Even for a first visit to primary care by severely depressed patients, antidepressants may not be the best treatment, the researchers say. “The best strategy may be to reframe some of the negative cognitions of the patients and advise physical activity,” writes Arroll, with follow-up to track the patients’ results.

This advice is similar to guidance issued in 2021 by the organization that develops standards for health care practices in England. The London-based National Institute for Health and Care Excellence advised doctors not to routinely prescribe antidepressants as first-line treatment for people with less severe depression, but to offer a variety of non-drug treatment options and to respect the patients’ right to decline treatment.

Recent studies have found little, if any, benefit to antidepressants over placebos. Researchers led by Marc B. Stone of the FDA’s Center for Drug Evaluation and Research combined the results of 232 randomized controlled trials reported to the FDA from 1979 to 2016 that compared the effect of selective serotonin reuptake inhibitor (SSRI) antidepressants with placebos for patients with depression. Publishing their report in 2022 in the British Medical Journal, the researchers found that a benefit from antidepressants over placebos was limited to just 15% of the patients, while the other 85% experienced no benefit as compared to placebos. The placebo effect was powerful, with roughly two-thirds of the depressed patients given placebos getting better.

Another 2022 study found no clinically significant difference in measures of depression symptoms between adults treated with antidepressants and those taking placebos, whether over a shorter or longer time frame and regardless of the depression severity of the study participants.

Some 45 million Americans are currently taking one or more antidepressants, including 5.7 million children and young adults under the age of 25, for whom the FDA requires a warning on the drug’s prescribing information of the increased risk of suicidal thoughts and actions.

Other adverse effects of antidepressants include weight gain, nausea, insomnia, agitation, emotional blunting and sexual dysfunction. One recent study found that half of antidepressant users experience sexual problems that can strain their relationships and lead to a worsening of their depression.  In a survey of antidepressant users, 44% of respondents reported the drugs negatively impacted their sex lives, 27% their ability to work or study, and 21% their relationships with friends or family.

Those who used antidepressants any time during the 30-year period of another recent study had an 81% greater chance of having more severe depression symptoms at the end of the study.

Antidepressants may be prescribed to prevent suicides, but an examination of coroner inquests in which the decedents used antidepressants revealed that about half of the deaths were determined to be suicides.  One in eight of the deaths involved an overdose of antidepressants.

Discontinuing antidepressants can bring on serious symptoms during withdrawal, including electric shock-like sensations (“brain zaps” and “body zaps”), muscle spasms and tremors, hallucinations, confusion, irritability, and mania. One study found that more than half (56%) of people attempting to come off antidepressants experience withdrawal symptoms, with nearly half (46%) of them describing those symptoms as severe, and the symptoms can last for weeks or months.

More fundamentally, a landmark 2022 study questioned the prescribing of antidepressants at all, after finding the common reason for taking them – to correct a chemical imbalance in the brain – had no scientific basis. The study investigated whether evidence supported the theory that a low level of the brain chemical serotonin causes depression.

“The serotonin theory of depression has been one of the most influential and extensively researched biological theories of the origins of depression,” the researchers wrote. “Our study shows that this view is not supported by scientific evidence. It also calls into question the basis for the use of antidepressants.”

WARNING: Anyone wishing to discontinue or change the dose of an antidepressant or other psychiatric drug is cautioned to do so only under the supervision of a physician because of potentially dangerous withdrawal symptoms.

The Citizens Commission on Human Rights (CCHR) continues to raise public awareness of the risks of serious side effects and withdrawal symptoms from antidepressants and other psychiatric drugs, so that consumers and their physicians can make fully informed decisions about starting or stopping the drugs. CCHR supports safe and science-based non-drug approaches to mental health.

CCHR also recommends a complete physical examination with lab tests, nutritional and allergy screenings, and a review of all current medications to identify any physical causes of depression or other unwanted mental and behavioral symptoms, which might otherwise be misdiagnosed and incorrectly treated as a psychiatric disorder.

The Citizens Commission on Human Rights was co-founded in 1969 by members of the Church of Scientology and the late psychiatrist and humanitarian Thomas Szasz, M.D., recognized by many academics as modern psychiatry’s most authoritative critic, to eradicate abuses and restore human rights and dignity to the field of mental health. CCHR has been instrumental in obtaining 228 laws against psychiatric abuse and violations of human rights worldwide.

The CCHR National Affairs Office in Washington, DC, has advocated for mental health rights and protections at the state and federal level. The CCHR traveling exhibit, which has toured 441 major cities worldwide and educated over 800,000 people on the history to the present day of abusive and racist psychiatric practices, has been displayed at the Congressional Black Caucus Foundation Annual Legislative Conference in Washington, DC, and at other locations.

Anne Goedeke
Citizens Commission on Human Rights, National Affairs Office

1701 20th St. NW

Washington, DC 20009

(202) 349-9267

Treatment Resistant Depression is Apparently a Thing

Monday, February 6th, 2023

Psychiatrists like to fund research studies for so-called “Treatment Resistant Depression” (TRD). They say that if someone has been given antidepressant drugs but their symptoms haven’t improved, they may have treatment-resistant depression.

Of course, the treatments of choice for TRD are more psychiatric drugs, such as ketamine and esketamine (dissociative anesthetics), olanzapine (an atypical anti-psychotic drug) and fluoxetine (Prozac). Some claim that Transcranial Magnetic Stimulation (TMS) or electroconvulsive therapy (ECT or shock treatment) “work” for this. Of course, all these “treatments” just knock your brain for a loop, so you don’t feel depressed, or much of anything anymore. None of these actually address the root causes for these symptoms, which psychiatrists conveniently forget to tell you.

One study suggests that between 29% and 46% of patients are still depressed after taking antidepressant drugs. Another study claims 20%-60% do not respond to psychiatric drugs. Well, we’ve known for years that not only is there no such “mental illness” as depression, but also that these mind-altering drugs don’t help.

People can, of course, experience symptoms commonly labeled as depression. In fact, there are hundreds of genuine medical conditions which can produce such mental symptoms — each of which has clinical tests and recognized medical treatments which do not involve psychiatric drugs.

While the fraudulent psychiatric “brain chemical imbalance” theory has been debunked for many years, it has been held firmly in place by the psycho-pharma public relations machine in order to sell more harmful and addictive psychiatric drugs. These drugs make patients for life since the drugs do not cure anything and have devastating side effects.

Psychiatrists have known since the beginning of psychopharmacology that their drugs do not cure any disease, and that antidepressants do not have any legitimate medical value. These are just public relations theories to support the marketing and sale of drugs. This is why the words “depressed” or “depressive” occur 77 times in various fraudulent diagnoses in the Diagnostic and Statistical Manual of Mental Disorders (DSM), in a vain attempt to legitimize this so-called “disease.”

Troubled patients being misled about what causes their problems and being told that they need to take a psychotropic drug to “correct” this is a form of coercion. Giving patients such misinformation prevents their making an informed decision and has already resulted in many millions of people taking antidepressants or other psychotropic drugs with harmful side effects, erroneously believing these would “correct” something that simply never existed.

These drugs mask the real cause of problems in life and debilitate the individual, so denying him or her the opportunity for real recovery and hope for the future. This is the real reason why psychiatry is a violation of human rights. Psychiatric treatment is not just a failure — it is routinely destructive to the individual and one’s mental health.

If you know someone who has bought into these lies, suggest they investigate non-psychiatric, non-drug alternatives. Contact your local, state and federal representatives and demand that they stop government funding of these drugs.

The Hoax of Antidepressants

Monday, July 4th, 2022

Over time, using antidepressants is not associated with significantly better health-related quality of life (HRQoL), compared to people with depression who do not take the drugs.

These are the findings of a study published April 20, 2022 in the journal PLOS ONE.

The study included all noninstitutionalized U.S. adults (?18 years) who had depression documented in their medical condition files during the first year of the two-year follow-up. Over the duration of the study (2005–2016), on average there were 17.47 million adult patients diagnosed with depression disorder every year with two-year follow up. About 57.6% of these patients received treatment with antidepressant drugs.

The researchers recommend that “Physicians, mainly primary care providers who are caring for most of these patients, may need to reconsider referring patients with depression to receive some kind of non-pharmacological therapy.”

The research study concludes with this quote:
“The ultimate goal of using antidepressant medications or psychotherapy is to improve patients’ important outcomes, such as HRQoL. The real-world effect of using antidepressant medications does not continue to improve patients’ HRQoL over time, as the change in HRQoL was comparable to patients who did not use any antidepressant medications.”

This is not even to mention the potentially horrific side effects of antidepressant use. The U.S. Food & Drug Administration (FDA) has this to say about antidepressant side effects: “Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents with MDD [major depressive disorder] and other psychiatric disorders.”

Recognize that the real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax — unscientific, fraudulent and harmful. All psychiatric treatments, not just psychiatric drugs, are dangerous.

If you are taking any of these drugs, do not stop taking them based on what you read here. You could suffer serious withdrawal symptoms. Click here for more information about harmful and addictive psychiatric drugs.

Psychiatrists euphemistically call withdrawal side effects “discontinuation symptoms” to disguise the addictive nature of these drugs.

You should seek the advice and help of a competent non-psychiatric medical doctor or practitioner before trying to come off any psychiatric drug.

Contact your local, state and federal officials and let them know your viewpoints about harmful psychiatric treatments.

The Suicide Risk Assessment Fraud

Monday, February 28th, 2022

“A disappointing, and perhaps the most telling, finding was that there has been no improvement in the accuracy of suicide risk assessment over the last 40 years.”

Suicide Risk Assessment doesn’t work. In fact, research suggests it not only doesn’t help, but also it may hurt.

One study looked at the last 40 years of suicide risk assessment research. They found no statistical method to identify patients at a high-risk of suicide in a way that would improve treatment.

Another study of people who had already harmed themselves found that there was no evidence to support the use of risk assessment scales.

Combined with ineffective suicide risk assessment, patients labeled with depression or suicidal ideation often receive prescriptions for dangerous psychotropic drugs laden, and even labeled, with side effects that encourage the exact symptoms they are marketed to treat.

Suicide prevention is a social issue, rather than a medical one. A psychiatrist prescribing an antidepressant is thus not really providing a valid treatment, and the widespread use of suicide risk assessment diverts social and health care practitioners from engaging with patients to find out and handle whatever is really the problem.

Risk assessments, screenings, school mental health programs and more funding are often presented as solutions to suicide, and since the onset of the Covid pandemic calls for more screenings and funding are louder than ever. Yet these so-called solutions are actually contributing to the problem by masking truly effective solutions and proliferating the use of psychotropic drugs whose side effects include suicide and violence.

No one denies that people can have difficult problems in their lives, that at times they can be mentally unstable. Mental health care is therefore both valid and necessary. However, the emphasis must be on workable mental healing methods that improve and strengthen individuals and thereby society by restoring people to personal strength, ability, competence, confidence, stability, responsibility and spiritual well-being. Psychiatry is not workable.

Tianeptine – An Alternative Worse Than Opioids

Monday, March 15th, 2021

Just when one might have thought that the U.S. was getting a handle on opioid addiction, another harmful and highly addictive opioid-like drug has appeared in widespread use.

The March 2021 issue of Consumer Reports has a comprehensive article about Tianeptine, an illegal drug linked to reports of harm, abuse and deaths.

Tianeptine acts in the brain as an opioid. The FDA says it is illegal and unsafe in the U.S., although it is approved as a prescription antidepressant in some European, Asian, and Latin American countries.

Reports indicate that tianeptine is even more addictive, with more severe withdrawal adverse reactions, than opioids and heroin.

Yet some proponents, possibly motivated by greed if not by malign intentions, are trying to get the FDA to approve it as a prescription drug for depression in the U.S.

Are You Depressed?

Psychiatry is heavily pushing false data about depression.

The fact is, the American Psychiatric Association, the American Medical Association and the National Institute of Mental Health admit that there are no medical tests to confirm mental disorders as a disease but do nothing to counter the false idea that these are biological/medical conditions when in fact, diagnosis is simply done by a checklist of behaviors.

People do experience symptoms of depression. But there are non-harmful, medical alternatives; addictive and harmful psychiatric drugs are not the solution.

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