Posts Tagged ‘antipsychotic’

Cap It Off With Caplyta

Monday, September 21st, 2020

Emerging from a cloud of regulatory questions and mixed clinical results, Caplyta (generic lumateperone) an atypical antipsychotic from Intra-Cellular Therapies, Inc. was given FDA approval 20 December 2019, and is now being heavily marketed. There are over a dozen of these second-generation antipsychotics, with varying activity at the brain receptors for various neurotransmitters.

It is hardly clear whether lumateperone has any advantages over other antipsychotic drugs. The primary reason for researching and releasing another atypical antipsychotic is to try to reduce the side effects, rather than to actually eliminate the symptoms, since no one really knows what causes these symptoms. The manipulation of neurotransmitters in the brain is just a guess, unfounded by any real understanding, just as the actual causes of so-called schizophrenia (psychiatry’s “For Profit Disease”) are not understood.

Side Effects of this dangerous drug include: stroke, neuroleptic malignant syndrome, tardive dyskinesia, diabetes, low white blood cell count, low blood pressure, falls, seizures, sleepiness, trouble concentrating, high temperature, difficulty swallowing, withdrawal symptoms in newborn babies exposed to Caplyta during the third trimester, pruritus (itchy skin), rash, urticaria (hives), increased mortality in elderly patients with dementia-related psychosis.

Patients are urged to avoid Cytochrome P450 (CYP3A4) inducers or inhibitors, since these may exacerbate the adverse reactions, causing violence and suicide.

List Price: $44 per 42mg capsule, with a peak sales estimate of $60 million in 2020 and $400 million by 2024. There may be conditions for insurance approval; for example, UnitedHealthcare may require the failure, contraindication, or intolerance to three other atypical antipsychotics before giving approval to pay for the use of Caplyta.

The antipsychotic activity of Caplyta is thought to be mediated through a combination of antagonism of serotonin receptors and antagonism of dopamine receptors in the brain, however the actual mechanism of action of Caplyta in schizophrenia is unknown.

Clinical trial results were measured by the opinion of a clinician observing or asking the patient about their feelings. The results require cautious interpretation and could represent chance findings. One phase III trial showed some symptomatic improvement and another phase III trial failed to show any improvement over placebo.

Obviously use this drug at your own serious risk, and insist on Full Informed Consent.

The real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax – unscientific, fraudulent and harmful. All psychiatric treatments, not just psychiatric drugs, are dangerous.

It is vital that patients watch the video documentary “Making A Killing – The Untold Story of Psychotropic Drugging“. Containing more than 175 interviews with lawyers, mental health experts, the families of psychiatric abuse victims and the survivors themselves, this riveting documentary rips the mask off psychotropic drugging and exposes a brutal but well-entrenched money-making machine. The facts are hard to believe, but fatal to ignore.

Schizo Christmas Present from the FDA

Sunday, December 29th, 2019
The US Food and Drug Administration (FDA) finally approved the new antipsychotic drug lumateperone (Caplyta, from Intra-Cellular Therapies, Inc) on December 23, 2019 for treatment of schizophrenia in adults, in spite of previously canceling its review because of mixed results in testing, which were blamed on positive responses to placebos.

As with other antipsychotics, lumateperone includes a boxed warning that elderly patients with dementia-related psychosis are at an increased risk for death.

Also as with other antipsychotics, the mechanism of action is unknown — they’re just guessing about how it is supposed to “work.” It plays Russian Roulette with serotonindopamine and glutamate (another neurotransmitter) in the brain.

It has all the usual possible side effects – neuroleptic malignant syndrome, tardive dyskinesia, hyperglycemia, diabetes, weight gain, sedation, increased risk of falls, seizures, infertility, etc.  Newborns exposed to antipsychotic drugs during the third trimester of pregnancy may suffer withdrawal symptoms.

Since cytochrome P450 enzymes such as CYP3A4 are involved in its metabolism in the liver, a person’s genetic abnormality with these can lead to the drug or its metabolites reaching a toxic level in hours or days, correlating with the onset of severe side effects. One is also ill-advised to drink grapefruit juice with this drug because it strongly inhibits the CYP3A4 enzyme, again increasing the risk of serious adverse reactions.

Of course, psychiatrists attribute any attempts at suicide to the underlying diagnosis and not to the drugs.

Speaking of the Underlying Diagnosis

Today, psychiatry clings tenaciously to antipsychotics as the treatment for “schizophrenia,” despite their proven risks and studies which show that when patients stop taking these drugs, they improve.

The late Professor Thomas Szasz stated that “schizophrenia is defined so vaguely that, in actuality, it is a term often applied to almost any kind of behavior of which the speaker disapproves.”

These are normal people with medical, disciplinary, educational, ethical or spiritual problems that can and must be resolved without recourse to drugs. Deceiving and drugging is not the practice of medicine. It is criminal.

Any medical doctor who takes the time to conduct a thorough physical examination of a child or adult exhibiting signs of what a psychiatrist calls Schizophrenia can find undiagnosed, untreated physical conditions. Any person labeled with so-called Schizophrenia needs to receive a thorough physical examination by a competent medical—not psychiatric—doctor to first determine what underlying physical condition is causing the manifestation.

Any person falsely diagnosed as mentally disordered which results in treatment that harms them should file a complaint with the police and professional licensing bodies and have this investigated. They should seek legal advice about filing a civil suit against any offending psychiatrist and his or her hospital, associations and teaching institutions seeking compensation.

No one denies that people can have difficult problems in their lives, that at times they can be mentally unstable, subject to unreasonable depression, anxiety or panic. Mental health care is therefore both valid and necessary. However, the emphasis must be on workable mental healing methods that improve and strengthen individuals and thereby society by restoring people to personal strength, ability, competence, confidence, stability, responsibility and spiritual well–being. Psychiatric drugs and psychiatric treatments are not workable.

For more information, click here to download and read the full CCHR report “Schizophrenia—Psychiatry’s For Profit ‘Disease’“.
Calvin and Hobbes

The Promise of Disordered Proteins

Monday, December 16th, 2019
Various biotechnology companies are betting on the therapeutic potential of a certain class of proteins in researching possible new drugs.

Such proteins, called “intrinsically disordered proteins” (IDPs), look different from the proteins with rigid structures that are more familiar in cells. IDPs are shape-shifters, appearing as ensembles of components that constantly change configurations. This loose structure allows the IDPs to bring together a wide variety of molecules at critical moments, such as during a cell’s response to stress. Less flexible proteins tend to have a more limited number of binding partners. When IDPs do not function properly, disease can ensue. Medical researchers have  been trying to create treatments to eliminate or regulate malfunctioning IDPs.

In 2017 researchers demonstrated that an FDA-approved drug called trifluoperazine (which is prescribed for psychotic disorders and anxiety) bound to and inhibited NUPR1, a disordered protein involved in a form of pancreatic cancer.

The NUPR1 (nuclear protein 1) gene is an intrinsically disordered protein coding gene which is associated with pancreatic cancer, although the details of such functions are still unknown.

Trifluoperazine (brand name Novo-Trifluzine) is an older antipsychotic, also called a Major Tranquilizer or Neuroleptic. As with all such antipsychotics, possible side effects are: akathisia, neuroleptic malignant syndrome, tardive dyskinesia, anxiety, depression, mood changes, hostility, pancreatitis, seizures, suicidal thoughts, and violence.

The point we want to make is that researchers are actively investigating psychotropic drugs to see if they can be re-purposed for other uses than for which the FDA currently approves. If such drugs, or offshoots of such drugs, are given permission to be prescribed for additional uses, then more people could be exposed to the side effects of such drugs.

“TFP [trifluoperazine] cannot be used in clinic for treating patients with cancer, due to the numerous undesirable side effects that occur at efficient anticancer doses.” Since TFP shows such strong central nervous system side effects, researchers try to develop TFP derivatives with less side effects. Of course, human clinical trials must be done to show the results before marketing a drug, since the research up to this point has been done on mice.

But again, the points we want to make are that 1) the details of how these drugs are supposed to “work” are often unknown; 2) this type of research is highly speculative; and 3) the base drugs have toxic side effects.

All this reflects back to the original use of such psychotropic drugs and their horrific side effects. And the point we really want to make about this is that the root problem is not even the drugs. The real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior or study problems as  “diseases,” using the fraudulent Diagnostic and Statistical Manual of Mental Disorders as justification to prescribe these drugs and other coercive and abusive “treatments.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax – unscientific, fraudulent and harmful. All psychiatric treatments, not just psychiatric drugs, are dangerous.

Decades of psychiatric monopoly over mental health has only lead to upwardly spiraling mental illness statistics, continuously escalating funding demands, and ever more addictive and harmful drugs which can cause violence and suicide.

The many critical challenges facing societies today reflect the vital need to strengthen individuals through workable, viable and humanitarian alternatives to harmful psychiatric options. Contact your local, state and federal representatives and let them know what you think about this.

Click here for more information.

Nursing Homes Abusing Dementia Patients with Antipsychotics

Monday, October 14th, 2019

A Human Rights Watch report found that many nursing homes are sedating their dementia residents by misusing antipsychotic drugs.

Former nursing home administrators admitted doling out drugs without having appropriate diagnoses, securing informed consent or divulging risks.

Having observed this personally for myself in a local St. Louis elder care facility, it is no surprise.

The report estimates that each week more than 179,000 elderly people living in U.S. nursing homes are fraudulently given antipsychotic drugs, without an approved psychiatric diagnosis, to suppress difficult behaviors and ease the load on overwhelmed staff.

This abusive practice benefits drugmakers to the tune of hundreds of millions of dollars, largely at the expense of the U.S. government.

Furthermore, the FDA has not deemed antipsychotic drugs an effective or safe way to treat symptoms associated with dementia. In fact, the FDA cautions that these drugs pose dangers for elderly patients with dementia, even doubling the risk of death.

Missouri’s antipsychotic use rate has remained around 18.5% or higher since 2016, and at 18.6 percent it’s now fifth worst in the nation.

Current research indicates that the fewer nurses available per patient, the more likely antipsychotics are to be improperly prescribed.

The shocking truth is that one in five seniors in the U.S. suffers from abusively prescribed psychoactive drugs. The psychiatric industry gets away with this abuse because they have fraudulently redefined old age as a “mental illness” in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and the International Classification of Diseases (ICD-11).

Examples of diagnoses that could be age-related

DSM-5: Phase of life problem, Problem related to living in a residential institution, Insufficient social insurance or welfare support, Alzheimer’s disease; and of course the catch-all Unspecified mental disorder

ICD-11: Various categories of Dementia; and in contrast to the DSM, the ICD just names it outright as Old age

A For-Profit Disease

To psychiatrists old age is a “mental disorder,” a for-profit disease for which they have no cure, but for which they will happily supply endless prescriptions of psychoactive drugs or electro-convulsive therapy. In most cases, the elderly are merely suffering from physical problems related to their age; for which psychiatry’s answer is to label them “depressed” or having “dementia.”

Through these fraudulent diagnoses, psychiatrists can involuntarily commit the elderly to a psychiatric facility, take control of their finances, override their wishes regarding their business, property or health care needs, and defraud their health insurance.

If an elderly person in your environment is displaying symptoms of mental trauma or unusual behavior, ensure that they get competent medical care from a non-psychiatric doctor. Insist upon a thorough physical examination to determine whether an underlying, undiagnosed physical problem is causing the condition.

For more information, download and read the CCHR bookletElderly Abuse – Cruel Mental Health Programs – Report and recommendations on psychiatry abusing seniors.

Schizophrenia: The Sacred Symbol of Psychiatry

Monday, October 7th, 2019

In 1976 Dr. Thomas Szasz, the co-founder of CCHR, published an article in The British Journal of Psychiatry called “Schizophrenia: The Sacred Symbol of Psychiatry,” in which Szasz argues that there is no such disease as schizophrenia.

Schizophrenia — the most common and most disabling of the so-called mental illnesses — has become the poster disease for psychiatry, the psychiatric symbol of why we need psychiatrists.

However, Szasz recognized that there are no clinical tests for such a “disease,” and that labeling the symptoms was rather psychiatry’s attempt to control deviant behavior rather than to cure disease.

Szasz stated that “schizophrenia is defined so vaguely that, in actuality, it is a term often applied to almost any kind of behavior of which the speaker disapproves.”

Psychiatrists today remain committed to labeling “schizophrenia” a mental disease despite, after a century of research, the complete absence of objective proof that it exists as a physical brain abnormality.

The unfortunate aspect of this is that psychiatry clings tenaciously to antipsychotics as the treatment for “schizophrenia,” despite their proven risks and studies which show that when patients stop taking these drugs, they improve.

Psychiatry is Enamored of Symbols

This deserves a more complete examination of the subject of “symbols.” We name, or label, objects and ideas, which in itself is not a bad thing, as long as we realize that the symbol is not the thing itself.

A symbol is something which has mass, meaning and mobility. An example is a body. We label a body with a name which we then use to mean the person; the body moves, carrying its mass and meaning around for others to see and experience.

On top of that, we label it “schizophrenic”, so we have a symbol of a symbol. Now we don’t have to directly confront the painful symptoms; we just label it “a schizophrenic.” We no longer have to cure it, since now we “know” what it is.

Psychiatry insists that one have a label, which is one way to trap and keep a person located. Using and being slaves to symbols is basically a substitute for just knowing. We no longer have to really know what it is, because we “know” it is “a schizophrenic.” So psychiatry has operated on this basis for over a hundred years, never really finding out what schizophrenia is so it can be cured. People just have to live with it, and take psychiatric drugs which are highly profitable and which suppress the symptoms but do not actually fix it.

Psychiatry Uses Other Symbols As Well

The psychiatric or psychological analysis of symbols in dreams has been a fruitless red herring for many centuries. It can certainly be interesting and fun to imagine all the ways dreams could be interpreted; but really, it doesn’t actually lead to cures. Dreams are mostly puns on words and situations.  Thiamine (vitamin B1) has been used successfully at doses of 250 mg/day to treat patients having nightmares. B1 at roughly $20 per bottle beats any anti-anxiety or anti-psychotic drug currently being prescribed for bad dreams, since one of the possible side effects of these drugs is (wait for it…) nightmares!

Now think of the Rorschach Ink Blot Test, originally developed in 1921 by Swiss psychologist Hermann Rorschach as a tool for the diagnosis and labeling of schizophrenia. Over the years several different scoring systems were used, including pure subjective judgment; one present day scoring system wasn’t developed until the 1960s, and another scoring system was published in 2011. There are naturally many critics of these systems, including some court cases calling the results bogus.

Given the fraudulent nature of psychiatric “diagnosis” in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and the International Classification of Diseases (ICD-11), we are calling the Rorschach symbol test a total hoax.

And Speaking of the DSM and the ICD

Of course, the names of so-called mental disorders in the DSM and ICD are the ultimate in misleading symbols. They appear to designate actual mental states, but upon close inspection they are empty of scientific meaning.

With these tomes, psychiatry has taken countless aspects of normal human behavior and reclassified them as a “mental illness” simply by adding the term “disorder” onto them. As the diagnoses completely lack scientific criteria, anyone can be labeled mentally ill, and subjected to dangerous and life threatening “treatments” based solely on opinion.

Though the DSM weighs less than five pounds, its influence pervades all aspects of modern American society: our governments, our courts, our military, our media and our schools.

Using it, psychiatrists can enforce psychiatric drugging, seize your children and even take away your most precious personal freedoms. It is the engine that drives a $330 billion psychiatric industry.

Missouri law explicitly names the DSM as the official reference for mental illnesses. Contact your State Senator and Representative and ask them to remove all references to the DSM from State Law. We should not support symbolism that hits you over the head; a symbol should not be a cymbal.

They say TD is Manageable; They Lie

Monday, July 15th, 2019

A recent spate of TV ads points to a new public relations campaign by the psychopharmaceutical mental health industry masquerading as a public service in an attempt to downplay the disastrous side effects of psychiatric drugs.

The tag line is “TD is Manageable“; TD being Tardive Dyskinesia [tardive, “late appearing” and dyskinesia, “abnormal muscle movement”], in which the muscles of the face and body contort and spasm involuntarily.

It has been known for a long time that the use of antipsychotics and other psychiatric drugs, prescribed for so-called schizophrenia and other fraudulent psychiatric diagnoses, may lead to tardive dyskinesia which causes random muscle movements that a person can’t control, and in some cases are permanent and cannot be cured.

Some research has also shown that TD may precipitate cognitive impairment.

On Feb. 11, 2014, a Chicago jury awarded $1.5 million to an autistic child who developed a severe case of irreversible tardive dyskinesia while being treated by psychiatrists with Risperdal and then Zyprexa between 2002 and 2007.

Since there is no known cure for TD, this public relations campaign is designed to make people feel that it isn’t so bad after all when the body jerks around for no reason. The best they can suggest is to talk to your doctor about it, reduce stress, and oh! by the way! you can also take this new psychiatric drug Ingrezza (generic valbenazine).

So, we finally see that this PR campaign is not really a public service, it’s about selling more psychiatric drugs.

Ingrezza from Neurocrine Biosciences, Inc. is believed to reduce dopamine release in the brain (they don’t really know how it “works”.)

The body must strictly regulate dopamine levels since both an excess and a deficiency can be problematic. Drugs which mess with dopamine play Russian roulette with your brain. And of course this drug has the usual range of adverse reactions, including akathisia (a movement disorder that makes it hard to stay still) which is just another form of TD.

The only real way to “manage” TD is not to get it in the first place by not taking any psychiatric drugs. Recognize that the real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases,” so that they can make a buck selling drugs whose side effects make you a patient for life. Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax — unscientific, fraudulent and harmful.

You’re Not Paranoid, It’s Really Happening

Monday, June 3rd, 2019

Abilify Mycite® (aripiprazole tablets with sensor, from Otsuka Pharmaceutical) is a prescription drug of an aripiprazole tablet (an atypical antipsychotic) with a metallic Ingestible Event Marker (IEM) sensor inside it, used in adults for diagnoses of schizophrenia, bipolar I disorder, and major depressive disorder. A month’s supply of it costs around $1,650. The actual mechanism of action of aripiprazole is unknown, although it messes with the levels of dopamine and serotonin in the brain, which is playing Russian Roulette with your mind.

The sensor is intended to track, with a smartphone app, if the drug has been taken. The ability of this drug to improve patient compliance or modify dosage has not been established. The only thing the FDA approved was functions related to tracking drug ingestion. The use of this drug to track drug ingestion in real-time or during an emergency is not recommended because detection may be delayed or not occur.

The drug sends information to a patch worn on the patient’s arm, which is then logged on a mobile app, which then sends the data to their doctor. Some experts warn that the idea of swallowing a tracking chip may be too much for paranoid patients to handle.

Said one expert, “I am concerned about the formation of new pharmaceutical persons who are digitally enhanced to be compliant with the profit motives of corporations and the directives of health providers and drug companies. … The fact that the drug is Abilify, which is prescribed to people who experience serious mental distress, should raise many ethical red flags. These concerns are especially relevant because the patent for the original Abilify drug expired in 2016… My concern is that … the company will be motivated to profit from the technology as much as possible, regardless of whether the drug actually improves health.”

The idea for this gross invasion of privacy comes about because refusing to take prescribed drugs is a particular psychiatric concern, and is even enshrined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) as “Nonadherence to medical treatment.”

Abilify MyCite is still not widely used in the US, possibly because of skepticism from patients, prescribing doctors and insurance providers, although Otsuka has collaborated with Magellan Health to roll the drug out to the US, and UnitedHealthcare has developed complex rules for insurance authorization.

This drug has potentially severe side effects including stroke; akathisia; neuroleptic malignant syndrome; tardive dyskinesia; unusual urges such as compulsive gambling, sex, eating, or shopping; seizures; suicidal thoughts or behaviors. Side effects may be considerably more severe with known CYP2D6 poor metabolizers (a Cytochrome P450 enzyme.)

This drug also has a Boxed Warning about an increased risk of suicidal thinking and behavior in children, adolescents and young adults.

Recognize that the real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax — unscientific, fraudulent and harmful.

If you are taking this drug, do not stop suddenly. You could suffer serious withdrawal symptoms. You should seek the advice and help of a competent medical doctor or practitioner before trying to come off any psychiatric drug.

The Psychiatric Scientific Double Standard

Saturday, March 30th, 2019

When it comes to psychiatric scientific research, there is a double standard that favors what makes money and disavows what does not make money. When we say “double standard” we mean some rule or principle which is unfairly applied in different ways to different groups or situations, or that favors one group or situation over another. The actual principle in question here is called “evidence-based science.”

Many scientists, particularly those in the psychiatric-pharmaceutical industry, mouth that they favor “evidence-based science” when in fact they favor what can make the most money regardless of the evidence.

A recent Scientific American editorial (“The WHO Takes a Reckless Step“, April, 2019) denigrates Traditional Chinese Medicine because it is purportedly not “evidence-based.”

Yet Scientific American promotes psychiatry and psychiatric drugs, when it knows that every psychiatric drug on the market has somewhere in its fine print a statement to the effect that “we don’t know how it works,” while the FDA approves these drugs based on so-called “evidence.”

Here are some representative quotes:

  • The fine print for Rexulti (brexpiprazole, an antipsychotic) says, “the exact way REXULTI works is unknown”.
  • The fine print for Latuda (lurasidone, an antipsychotic) says, “It’s not known exactly how LATUDA works, and the precise way antipsychotics work is also unknown”.
  • The fine print for Xanax (alprazolam, a benzodiazepine anti-anxiety drug) says, “Their exact mechanism of action is unknown”.

So much for evidence-based practice! The actual evidence is, they don’t have a clue how these drugs are supposed to work — it’s all conjecture!

As we continue to examine the actual evidence, we come up against the adverse reactions, or side effects, of these drugs. This is hard evidence, not conjecture.

What is a Side Effect?

Side effects (also called “adverse reactions”) are the body’s natural response to having a chemical disrupt its normal functioning.

One could also say that there are no drug side effects, these adverse reactions are actually the drug’s real effects; some of these effects just happen to be unwanted.

The FDA takes the adverse side effect of suicide seriously by placing a Black Box Warning on certain psychiatric drugs. For example, the FDA says that “Antidepressants increase the risk of suicidal thinking and behavior (suicidality) in children and adolescents with MDD [Major Depressive Disorder] and other psychiatric disorders.”

What about those who say psychotropic drugs really did make them feel better? Psychotropic drugs may relieve the pressure that an underlying physical problem could be causing but they do not treat, correct or cure any physical disease or condition. This relief may have the person thinking he is better but the relief is not evidence that a psychiatric disorder exists. Ask an illicit drug user whether he feels better when snorting cocaine or smoking dope and he’ll believe that he is, even while the drugs are actually damaging him. Some drugs that are prescribed to treat depression can have a “damping down” effect. They suppress the physical feelings associated with “depression” but they are not alleviating the condition or targeting what is causing it.

Once the drug has worn off, the original problem remains. As a solution or cure to life’s problems, psychotropic drugs do not work.

For the first time the side effects of psychiatric drugs that have been reported to the U.S. Food and Drug Administration (FDA) by doctors, pharmacists, other health care providers and consumers have been decrypted from the FDA’s MedWatch reporting system and been made available to the public in an easy to search psychiatric drug side effects database and search engine. This database is provided as a free public service by the mental health watchdog, Citizens Commission on Human Rights International (CCHR).

Are You Schizophrenic?

Friday, January 18th, 2019

“Mental health advocates are lobbying Congress to help them get schizophrenia classified as a brain disease like Parkinson’s or Alzheimers, instead of as a mental illness, a move that could reduce stigma and lead to more dollars for a cure.” This according to a January, 2019 article on Politico.com.

More and more health officials, scientists and doctors are recognizing that so-called “mental illnesses” such as schizophrenia and bipolar disorder are poorly understood and are really physical, medical issues — not some nebulous mental thing for which harmful and addictive psychotropic drugs are prescribed.

There are no clinical tests for these “mental” diagnoses. But there are clinical tests for whatever turns out to be the real medical issue. So why are psychiatrists handing out so many harmful drugs without performing blood or other well-known clinical tests? Could it be because it is profitable, and insurance will pay for them?

Today, psychiatry clings tenaciously to antipsychotics as the treatment for “schizophrenia,” despite their proven risks and studies which show that when patients stop taking these drugs, they improve.

Linda Stalters, executive director of the schizophrenia alliance, said, “We are still treating people like they did in the medieval times.”

The late Professor Thomas Szasz stated that “schizophrenia is defined so vaguely that, in actuality, it is a term often applied to almost any kind of behavior of which the speaker disapproves.”

These are normal people with medical, disciplinary, educational, or spiritual problems that can and must be resolved without recourse to drugs. Deceiving and drugging is not the practice of medicine. It is criminal.

Any medical doctor who takes the time to conduct a thorough physical examination of someone exhibiting signs of what a psychiatrist calls schizophrenia can find undiagnosed, untreated physical conditions. Any person labeled with so-called schizophrenia needs to receive a thorough physical examination by a competent medical—not psychiatric—doctor to first determine what underlying physical condition is causing the manifestation.

Any person falsely diagnosed as mentally disordered which results in treatment that harms them should file a complaint with CCHR, the police, and professional licensing bodies and have this investigated. They should seek legal advice about filing a civil suit against any offending psychiatrist and his or her hospital, associations and teaching institutions seeking compensation. In Missouri, file a complaint with the Board of Registration for the Healing Arts.

No one denies that people can have difficult problems in their lives, that at times they can be mentally unstable, subject to unreasonable depression, anxiety or panic. Mental health care is therefore both valid and necessary. However, the emphasis must be on workable mental healing methods that improve and strengthen individuals and thereby society by restoring people to personal strength, ability, competence, confidence, stability, responsibility and spiritual well–being. Psychiatric drugs and psychiatric treatments are not workable.

For more information, click here to download and read the full CCHR report “Schizophrenia—Psychiatry’s For Profit ‘Disease’“.

Rexulti Fails to Get Results

Monday, November 26th, 2018

REXULTI (generic brexpiprazole) is a prescription psychiatric drug from Otsuka Pharmaceutical Company and Lundbeck pharmaceutical company. Although it failed Phase II clinical trials for attention-deficit hyperactivity disorder (ADHD), it was approved by the U.S. Food and Drug Administration (FDA) in 2015 as an atypical antipsychotic and prescribed for the fake “disease” schizophrenia.

Then in 2018 the FDA approved it to treat symptoms of depression when antidepressants alone do not relieve symptoms.

The cost for Rexulti oral tablet 0.25 mg is around $1,166 for a supply of 30 tablets. It has similarities to Abilify, and apparently it was developed to replace Abilify when that drug’s patent expired in 2014.

Brexpiprazole affects the levels of the neurotransmitters dopamine and serotonin in the brain. It is thought to reduce dopamine output when dopamine concentrations are high and increase dopamine output when dopamine concentrations are low. It also activates serotonin receptors to increase serotonin levels in a manner thought to reduce hallucinogenic effects, which is a problem with all drugs that mess with serotonin in the brain.

The metabolism of the drug — that is, the mechanism which eventually eliminates it from the body — is mediated by Cytochrome P450 enzymes; people who are known poor metabolizers, i.e. those with a genetic lack of these enzymes, should be instructed to take half the usual dose, although this is rarely done, since the patient must first be tested for this genetic condition. It is estimated that 10% of Caucasians and 7% of African Americans are Cytochrome P450 deficient. The consequences for someone with this deficiency who takes this drug are an increased risk for the accumulation of the non-metabolized drug in the body and the resultant increase in adverse side effects such as depression, violence and suicide.

Drugs like Rexulti can raise the risk of death in the elderly, and it is not approved for the treatment of patients with dementia-related psychosis. This drug may also increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment. It is not approved for the treatment of people younger than 18 years of age.

Rexulti may cause other serious side effects, including: compulsive, uncontrollable behaviors such as gambling, shopping, binge eating and sex (the same as with Abilify); stroke in elderly people; Neuroleptic Malignant Syndrome; high fever; stiff muscles; confusion; sweating; changes in pulse, heart rate, or blood pressure; high blood sugar (hyperglycemia); weight gain; seizures; difficulty swallowing; uncontrolled body movements known as tardive dyskinesia. Tardive dyskinesia may not go away, even after one stops taking the drug, and tardive dyskinesia may also start some time after one stops taking the drug.

The real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax – unscientific, fraudulent and harmful. All psychiatric treatments, not just psychiatric drugs, are dangerous. Find Out! Fight Back!