Rexulti Fails to Get Results

REXULTI (generic brexpiprazole) is a prescription psychiatric drug from Otsuka Pharmaceutical Company and Lundbeck pharmaceutical company. Although it failed Phase II clinical trials for attention-deficit hyperactivity disorder (ADHD), it was approved by the U.S. Food and Drug Administration (FDA) in 2015 as an atypical antipsychotic and prescribed for the fake “disease” schizophrenia.

Then in 2018 the FDA approved it to treat symptoms of depression when antidepressants alone do not relieve symptoms.

The cost for Rexulti oral tablet 0.25 mg is around $1,166 for a supply of 30 tablets. It has similarities to Abilify, and apparently it was developed to replace Abilify when that drug’s patent expired in 2014.

Brexpiprazole affects the levels of the neurotransmitters dopamine and serotonin in the brain. It is thought to reduce dopamine output when dopamine concentrations are high and increase dopamine output when dopamine concentrations are low. It also activates serotonin receptors to increase serotonin levels in a manner thought to reduce hallucinogenic effects, which is a problem with all drugs that mess with serotonin in the brain.

The metabolism of the drug — that is, the mechanism which eventually eliminates it from the body — is mediated by Cytochrome P450 enzymes; people who are known poor metabolizers, i.e. those with a genetic lack of these enzymes, should be instructed to take half the usual dose, although this is rarely done, since the patient must first be tested for this genetic condition. It is estimated that 10% of Caucasians and 7% of African Americans are Cytochrome P450 deficient. The consequences for someone with this deficiency who takes this drug are an increased risk for the accumulation of the non-metabolized drug in the body and the resultant increase in adverse side effects such as depression, violence and suicide.

Drugs like Rexulti can raise the risk of death in the elderly, and it is not approved for the treatment of patients with dementia-related psychosis. This drug may also increase suicidal thoughts or actions in some children, teenagers, or young adults within the first few months of treatment. It is not approved for the treatment of people younger than 18 years of age.

Rexulti may cause other serious side effects, including: compulsive, uncontrollable behaviors such as gambling, shopping, binge eating and sex (the same as with Abilify); stroke in elderly people; Neuroleptic Malignant Syndrome; high fever; stiff muscles; confusion; sweating; changes in pulse, heart rate, or blood pressure; high blood sugar (hyperglycemia); weight gain; seizures; difficulty swallowing; uncontrolled body movements known as tardive dyskinesia. Tardive dyskinesia may not go away, even after one stops taking the drug, and tardive dyskinesia may also start some time after one stops taking the drug.

The real problem is that psychiatrists fraudulently diagnose life’s problems as an “illness”, and stigmatize unwanted behavior as “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax – unscientific, fraudulent and harmful. All psychiatric treatments, not just psychiatric drugs, are dangerous. Find Out! Fight Back!

High Anxiety

We recently watched the classic Mel Brooks movie “High Anxiety.” Besides the fact that it is absolutely hilarious, and relentlessly parodies psychiatry and psychiatrists, it also leads into a discussion of anxiety as popularized by psychiatry and psychology.

The American Psychological Association says, “Anxiety is an emotion characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure. People with anxiety disorders usually have recurring intrusive thoughts or concerns. They may avoid certain situations out of worry. They may also have physical symptoms such as sweating, trembling, dizziness or a rapid heartbeat.”

The American Psychiatric Association says, “Anxiety is a normal reaction to stress … Anxiety disorders differ from normal feelings of nervousness or anxiousness, and involve excessive fear or anxiety.” But they go further and list many different types of anxiety disorders. The Diagnostic and Statistical Manual of Mental Disorders (DSM) lists no fewer than 54 disorders using the word “anxiety,” plus a number of other disorders with different names but which may still be considered as a type of anxiety disorder.

Psychiatrist Dr. Richard H. Thorndyke, played by Mel Brooks in the movie, suffers from “high anxiety,” manifested as vertigo ostensibly from a fear of heights, which in the DSM would be a “Specific phobia.”

The English word “anxiety” itself means, among other definitions, “apprehensive uneasiness, worry, or nervousness typically over an impending or anticipated ill, or something with an uncertain outcome.” [Latin anxietas, from anxius, from angere “to choke”]

Psychiatrists and psychologists attempt to give it a “medical” definition, which is necessary in order to prescribe drugs for it. One medical dictionary says this, “Anxiety disorder: A chronic condition characterized by an excessive and persistent sense of apprehension, with physical symptoms such as sweating, palpitations, and feelings of stress. Treatments include the comfort offered by understanding the condition, avoiding or desensitizing exacerbating situations, and medications.” Google says this, “a nervous disorder characterized by a state of excessive uneasiness and apprehension, typically with compulsive behavior or panic attacks.”

The relationship of anxiety to stress should be self-evident. You might like to review what we have written previously about stress.

Anxiety, like stress, is not a mental illness, and cannot be fixed with a drug. It can only be fixed by finding and eliminating the causes of the condition. For example, many doctors and nutritionists are finding that anxiety attack symptoms can be the result of food allergies. There are many other potential causes. We recommend a full, searching clinical examination by a competent non-psychiatric doctor, to find out if there are any undiagnosed and untreated actual medical conditions.

There is an international nonprofit organization called “Anxiety and Depression Association of America”, whose purpose is the prevention, treatment, and cure of anxiety and other “co-occurring  disorders.” Naturally they claim, falsely, that anxiety disorders have a biological basis, giving them a reason to prescribe drugs. The National Institute of Mental Health says, “Anxiety disorders are generally treated with psychotherapy, medication, or both.”

If you were thinking of an anti-anxiety drug, be warned that these can cause hallucinations, delusional thinking, confusion, aggression, violence, hostility, agitation, irritability, depression and suicidal thinking. They are also some of the most difficult drugs to withdraw from.

Anxiety is an emotion, and is really a conflict, or the restimulation of a conflict, or something containing indecision or uncertainty. It is exemplified by a conflict between something supporting survival and something opposing survival. It is rooted in an inability to assign the correct cause to something, which itself is rooted in an inability to observe. As we said, the cure is not a drug, but in finding out the correct cause.

Be Well.

More About Dopamine

Since we discussed Serotonin in a previous newsletter, we should also discuss Dopamine.

Dopamine is a neurotransmitter that plays several important roles in the brain and body. A neurotransmitter is a chemical released by neurons (nerve cells) to send signals to other nerve cells. Its chemical formula is C8H11NO2. It belongs to a family of chemicals with high psychoactive properties.

Dopamine was first synthesized in 1910, first identified in the human brain in 1957, and its function as a neurotransmitter was first recognized in 1958. The name comes from a contraction of chemicals in its synthesis.

The anticipation of rewards increases the level of dopamine in the brain, and many addictive drugs increase dopamine release or block its reuptake into neurons following release.

Dopamine has other effects around the body:

  • helps widen blood vessels
  • helps increase urine output
  • helps regulate insulin production
  • helps to protect the gastrointestinal tract
  • helps control motor function
  • helps regulate aggression

Because it seems to be involved in the anticipation of rewards, it is seen as a chemical of pleasure or happiness. Most antipsychotic drugs are dopamine antagonists which reduce dopamine activity. Decreased levels of dopamine have also been associated with painful symptoms. Like serotonin, dopamine levels must be strictly regulated since both an excess and a deficiency can be problematic.

Side effects of dopamine include lowered kidney function and irregular heartbeats, addiction, and an overdose can be fatal. Cocaine, methamphetamine, Adderall, Ritalin, Concerta, MDMA (ecstasy) and other psychostimulants generally increase dopamine levels in the brain by a variety of mechanisms.

Dopamine and serotonin are both neurotransmitters; an imbalance of either one can have disastrous effects on health, mental health, digestion, sleep cycle, and so on. The serotonergic system has strong anatomical and functional interactions with the dopaminergic system. While they both affect a lot of the same parts of the body, they do so in distinct ways which are still not fully understood. In the brain in general, dopamine is an excitatory neurotransmitter and serotonin is an inhibitory neurotransmitter. The imbalance of these two chemicals can cause a number of disorders; thus, drugs which mess with either of these play Russian roulette with your brain.

Because both serotonin and dopamine are involved in regulating aggression in different ways, one can see that imbalances can lead to suicidal thoughts and behaviors, which is a common side effect of drugs which mess with these neurotransmitters.

Researchers still only conjecture about any relationship between mental symptoms and dopamine, and they are coming to understand that the results do not support the hype.

Psychiatrists have known since the beginning of psychopharmacology that their drugs do not cure any disease. Further, there is no credible evidence that mental health is genetic or linked to dopamine transport; these are just public relations theories to support the marketing and sale of drugs. The manufacturers of every such drug state in the fine print that they don’t really understand how it works. Psychiatric drugs are fraudulently marketed as safe and effective for the sole purpose of earning billions for the psycho-pharmaceutical industry.

These drugs mask the real cause of problems in life and debilitate the individual, so denying him or her the opportunity for real recovery and hope for the future. This is the real reason why psychiatry is a violation of human rights. Psychiatric treatment is not just a failure — it is routinely destructive to the individual and one’s mental health.

You May Be Seeing Things That Aren’t Really There

But You Can See The Wool Being Pulled Over Your Eyes

Hallucinations and delusions are possible complications of Parkinson’s disease (PD). They are often referred to as PD psychosis. It’s estimated to occur in up to 50 percent of people with PD.

Hallucinations during PD can be frightening and debilitating. There are many factors that can contribute to hallucinations in people with PD, but the majority of cases occur as side effects of PD drugs.

Psychotic symptoms are related to high levels of a neurotransmitter known as dopamine, which is often one of the adverse reactions of psychiatric drugs.

There are many drugs that may contribute to hallucinations or delusions in people with PD, including sedatives and anti-seizure drugs.

Another danger is that a person experiencing PD psychosis may be misdiagnosed with schizophrenia and prescribed antipsychotics which may cause serious side effects and can even make hallucinations and delusions worse.

In 2016 the U.S. Food and Drug Administration (FDA) approved the antipsychotic drug pimavanserin (Nuplazid) specifically for use in PD psychosis because it does not alter levels of dopamine in the brain as much as other antipsychotics.

However, Acadia Pharmaceutical’s antipsychotic drug pimavanserin is now facing public scrutiny and fiscal uncertainty after a report from CNN in April 2018 detailed the deaths of more than 700 patients prescribed this drug since June 2016. You may be seeing advertisements for pimavanserin (Nuplazid) now in an attempt to reverse its negative publicity.

The exact mechanism of action of pimavanserin is unknown; however, it messes with the level of serotonin in the brain like other antipsychotics do. Special dosing requirements are necessary when other drugs being given along with pimavanserin have strong CYP450 interactions.

Nuplazid carries the black box warning “Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.” It also has a known adverse reaction of hallucinations with 5% of those taking it, which is exactly what it is supposed to prevent. Since no one knows how it is really supposed to work, it is just a guess based on what is observed during clinical trials, with the hope that its side effects won’t be too drastic, and that enough of it can be sold before the outcry against its adverse side effects becomes loud enough to ban it.

It’s just another harmful psychiatric drug whose purpose is to make money at the expense of vulnerable people, and make more patients for life due to its damaging side effects. Click here for more information about these harmful psychiatric drugs.

Psychiatric Drugs, School Violence, and Big Pharma Cover-Up

A study published June 12, 2018 from the University of Illinois at Chicago suggests that more than one-third (37.2%) of U.S. adults may be using prescription drugs that have the potential to cause depression or increase the risk of suicide.
[JAMA. 2018;319(22);2289-2298. doi:10.1001/jama.2018.6741]

Information about more than 26,000 adults from 2005 to 2014 was analyzed, along with more than 200 commonly prescribed drugs. However, many of these drugs are also available over the counter, so these results may underestimate the true prevalence of drugs having side effects of depression.

In other words, the use of prescription drugs, not just psychiatric drugs, that have depression or suicide as a potential adverse reaction is fairly common, and the more drugs one takes (called polypharmacy), the greater the likelihood of depression occurring as a side effect. “The likelihood of concurrent depression was most pronounced among adults concurrently using 3 or more medications with depression as a potential adverse effect, including among adults treated with antidepressants.”

Approximately 15% of adults who used three or more of these drugs concurrently experienced symptoms of depression or suicidal thoughts, compared with just 5% for those not using any of these drugs. Roughly 7.6% of adults using just one of these drugs reported a side effect of depression or suicidal thoughts during the study period, and 9% for those using two of these drugs. These results were the same whether the drugs were psychotropic or not. Depression was determined by asking nine questions related to the symptoms defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).

“Commonly used depression screening instruments, however, do not incorporate evaluations of prescribed medications that have depression as a potential adverse effect.” In other words, so-called depression screening tests can register false positives when the person is taking one or more of roughly 200 prescription drugs.

We thought we should dig a little deeper into this phenomenon.

First, understand that there is no depression “disease”. A person can certainly have symptoms of feeling depressed, but this is not a medical condition in itself. An example of a medical condition with a symptom of depression would be a vitamin B1 (thiamine) deficiency. You don’t fix it with an antidepressant; you fix it with vitamin B1. There are hundreds of medical conditions that may have mental symptoms, just as there are hundreds of drugs that can cause or worsen these symptoms. Finding the actual causes with appropriate clinical tests and then fixing what is found is the correct way to proceed.

This leads to a topic known as CYP450, which stands for Cytochrome P450 enzymes. Cytochrome means “cellular pigment” and is a protein found in blood cells. Scientists understand these enzymes to be responsible for metabolizing almost half of all drugs currently on the market, including psychiatric drugs.

These are the major enzymes involved in drug metabolism, which is the breakdown of drugs in the liver or other organs so that they can be eliminated from the body once they have performed their function.

If these drugs are not metabolized and eliminated once they have done their work, they build up and become concentrated in the body, and then act as toxins. The possibility of harmful side effects, or adverse reactions, increases as the toxic concentration increases. The ballpark estimate is that each year 2.2 million Americans are hospitalized for adverse reactions and over 100,000 die from them.

Some people are deficient in CYP450 or have diminished capacity to metabolize these drugs, which may be a genetic or other issue. Individuals with no or poorly performing CYP450 enzymes are much more likely to suffer the side effects of prescription drugs, particularly psychiatric drugs known to have side effects of depression, violence and suicide.

These metabolic processes are immature at birth and up to three years old, and this may result in an increased risk for drug toxicity in infants and young children. Furthermore, certain drugs or certain excipients in vaccines may inhibit activation of CYP450 enzymes, again resulting in an increased risk for the accumulation of non-metabolized drugs and the resultant increase in adverse side effects such as depression, violence and suicide.

The side effects caused by a CYP450 deficiency and its subsequent failure to metabolize any one of hundreds of drugs can then be misdiagnosed as a mental illness, the patient then being prescribed more psychiatric drugs in a mistaken attempt to treat those side effects, further complicating the problems.

It is estimated that 10% of Caucasians and 7% of African Americans are Cytochrome P450 deficient.

The psychiatric and pharmaceutical industries have been aware of this phenomenon for some time, yet they have continued to push psychiatric drugs at an ever increasing rate, and the dramatic increase in symptoms of depression, suicide, and school violence is a direct result.

No one should be prescribed these types of drugs without adequate testing for a CYP450 deficiency, in order to determine their risk potential for adverse reactions. The test is not “standard of care” so one has to ask for it; but beware, they will still recommend an alternative drug if the original one cannot be easily metabolized. Better yet, stop prescribing all psychiatric drugs and find out with proper medical, clinical tests what the real problems are and treat those. Full informed consent is always indicated.

Any psychiatrist or pharmaceutical company that has knowingly withheld evidence about the relationship between CYP450 enzymes and drug side effects should be subject to both prosecution and litigation.

Medical students should be educated about these relationships.

For more information click on any of the links in this newsletter.

Cannabidiol (CBD) – Can We Be Sure It’s Safe?

Every time we say “CBD” out loud we think Bidi Bidi and picture Buck Rogers’ Twiki the Robot.

But really, what is CBD, and is it harmful or helpful?

Derived from Cannabis (marijuana), CBD is one of many cannabinoids which are chemical compounds capable of binding to specific biological receptors in the brain or other sites in the body.

The theory is that when CBD binds to these brain receptors it seems to suppress or limit the immune system’s inflammatory signals.

Another cannabinoid, THC (tetrahydrocannabinol, also called “The High Causer”), is the principal psychoactive component of marijuana, and when it binds to receptors in the brain it gets you high. We also know that THC damages the immune system, yet proponents of cannabis call it a “medicinal herb.” Click here for more information about the harmful effects of this “herb.”

CBD and THC are structural isomers, which means they share the same chemical composition but their atomic arrangements differ.

The claim is that CBD, unlike THC, is not hallucinogenic. Much of the research information so far available about CBD comes from animal studies.

Although it is a cannabinoid, CBD apparently does not directly interact with the principal receptors in the brain to which THC binds, and binds to many other non-cannabinoid receptors in the brain.

Basically, the research to date is unclear on exactly how CBD works, except that we know it affects the brain. We’d call these observations mostly anecdotal — that is, people have reported on their observations and feelings, but the double-blind human clinical trials are sparse.

Animal studies have demonstrated that CBD directly activates multiple serotonin receptors in the brain, and we know that in humans at least, psychiatric drugs which mess with serotonin levels in the brain are addictive and have some disastrous side effects. The manufacturers of every psychiatric drug so far which messes with serotonin in the brain say they don’t really know how it works.

CBD, LSD, mescaline, and other hallucinogenic drugs bind to the same serotonin receptors in the brain, so calling CBD totally non-intoxicating is a bit of a stretch. We think the insistence on calling CBD “non-intoxicating” or “non-hallucinogenic” is Public Relations for “Bidi bidi, gee, we can make a bundle with this.” While the anecdotal evidence claims no hallucinogenic effect for CBD, the fact that it affects serotonin in the brain makes it less attractive as a healthy alternative. Its long-term effects are simply unknown.

Some proponents promote taking THC and CBD together. We think this is a short path to becoming a bidi bidi robot.

At higher dosages, CBD will deactivate cytochrome P450 enzymes, making it harder to metabolize certain drugs and toxins, particularly psychiatric drugs.

What about CBD oil or cream (hemp extract) applied to the skin? Is there a difference between CBD derived from hemp and CBD derived from marijuana?

CBD is legally available in the United States, but it must be derived from imported high-CBD, low-THC hemp. CBD itself is not listed under the Controlled Substances Act, so it’s legal in all 50 states provided it’s not extracted from marijuana.

A huge amount of fiber hemp is required to extract a small amount of CBD, so researchers are focused on breeding plants with more CBD and less THC just for this purpose. It is important to note that all cannabidiol products are not approved by the FDA for the diagnosis, cure, mitigation, treatment, or prevention of any disease.

CBD and THC both interact with the body through a vital nerve signaling system which regulates a wide array of functions, some of which include: pain, appetite, mood, memory, immune response, and sleep. There are still very little long-term safety data available. The proponents of CBD, whether for internal or external use, ignore the fact that it messes with serotonin when making claims for its safety and usefulness, so caution is advised. There is a lot of money riding on making these substances legal and ubiquitous; any bad effects are not going to be advertised or promoted.

At present, we’d prefer not to experiment with substances that tweak the brain in ways that are not fully understood, lest we become like bidi bidi Twiki. As always, your fully informed consent for any treatment is of paramount importance.

Nuedexta, PCP in Disguise

Nuedexta (dextromethorphan hydrobromide and quinidine sulfate) marketed by Avanir Pharmaceuticals is FDA approved for the treatment of PseudoBulbar Affect (PBA), a so-called neurological condition thought to cause involuntary, sudden, and frequent episodes of crying and/or laughing, observed with patients having amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), strokes, or traumatic brain injury. It was originally approved in 2010 by the FDA for such emotional instability.

Dextromethorphan may cause serotonin syndrome, a buildup of an excessive amount of serotonin in the body, and this risk is increased by overdose, particularly if taken with other serotonergic agents, SSRIs or tricyclic antidepressants.

Side effects of serotonin syndrome can be altered mental status, muscle twitching, confusion, high blood pressure, fever, restlessness, sweating, tremors, or shivering. Use of Nuedexta with selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants increases the risk of these side effects.

These are not all the possible side effects.

The quinidine in the formula is used to suppress metabolism of the dextromethorphan in order to increase the bioavailability of the dextromethorphan, and is not part of the treatment for PBA. Dextromethorphan acts on the central nervous system, but the mechanism by which dextromethorphan exerts any therapeutic effects in patients with PBA is totally unknown — it’s just a guess from clinical observations that it might have such a symptomatic effect.

Dextromethorphan, derived from an opioid analgesic, is sometimes referred to as DXM or the poor man’s PCP (phencyclidine, or Angel Dust), and is also used recreationally — acting as a dissociative anesthetic producing hallucinogenic states, delusions, or paranoia. At high concentrations, DXM can result in a false-positive for PCP on a drug screen. It is a nonselective serotonin reuptake inhibitor. Its previous primary use since 1958 is as a cough suppressant. Regular use over a long period of time can cause withdrawal symptoms. DXM is often used as a substitute for marijuana, amphetamine, and heroin by drug abusers, and its use as an antitussive (cough suppressant) is now known to be less beneficial than originally thought.

We think that part of the danger of this drug is that it can be prescribed for various symptoms in the Diagnostic and Statistical Manual of Mental Disorders (DSM) just because of its claims of symptomatic relief — in spite of the fact that its mechanism of operation is unknown, its use can be severely abused, and its side effects can be fatal; and the symptoms of its side effects as well as the original medical issues can lead to the prescription of other dangerous and addictive psychiatric drugs.

Examples of DSM diagnoses that may be involved are “Histrionic personality disorder”, “High expressed emotion level within family”, “Adjustment disorder, With mixed disturbance of emotions and conduct”, and “Unspecified mental disorder due to another medical condition”.

Nuedexta is not thought of or advertised as a psychotropic drug, but exposing its camouflage one can now see that essentially it is psychoactive and should be avoided — another example of a psychiatric drug disguised as a legitimate medical drug.

Click here for more information about dangerous psychiatric drugs.

Many People Taking Antidepressants Discover They Cannot Quit

The New York Times had an article April 7, 2018 discussing the fact that antidepressants are actually addictive and have withdrawal symptoms. Quotes are from this article.

“As far back as the mid-1990s, leading psychiatrists recognized withdrawal as a potential problem for patients taking modern antidepressants.”

On the other hand, CCHR has been making this known since 1969. Psychiatrists have been loathe to admit the addictive nature of antidepressants and other psychotropic (mind-altering) drugs, and euphemistically call the side effects of withdrawing from psychiatric drugs “discontinuation syndrome”.

Drug addiction in the 1960’s became an increasing problem, and when investigated it was found that psychiatrists were pushing drugs and addicting people as a “cure.”

“Long-term use of antidepressants is surging in the United States, according to a new analysis of federal data by The New York Times. Some 15.5 million Americans have been taking the medications for at least five years. The rate has almost doubled since 2010, and more than tripled since 2000.”

Nearly 25 million adults have been on antidepressants for at least two years, a 60 percent increase since 2010.

“Many who try to quit say they cannot because of withdrawal symptoms they were never warned about.”

We recommend Informed Consent. Protect yourself, your family and friends, with full informed consent. Courts have determined that informed consent for people who receive prescriptions for psychotropic (mood-altering) drugs must include the doctor providing information about possible side effects and benefits, ways to treat side effects, and risks of other conditions, as well as information about alternative treatments.

“Antidepressants are not harmless; they commonly cause emotional numbing, sexual problems like a lack of desire or erectile dysfunction and weight gain.”

“Patients who try to stop taking the drugs often say they cannot. In a recent survey of 250 long-term users of psychiatric drugs — most commonly antidepressants — about half who wound down their prescriptions rated the withdrawal as severe. Nearly half who tried to quit could not do so because of these symptoms.”

“The truth is that the state of the science is absolutely inadequate … We don’t have enough information about what antidepressant withdrawal entails, so we can’t design proper tapering approaches.”

Polypharmacy is another significant problem, wherein a patient is prescribed many, possibly negatively-interacting drugs, often by multiple doctors who might be unaware of each other’s prescription orders. Often, these are drugs that the patient has been taking for a long period; they may be affecting the patient’s health negatively or are simply no longer beneficial. This is often addressed by deprescribing, which is the process of reducing the medication burden of a patient who might no longer need one or more of their prescriptions. Deprescribing principles are intended to improve health care for the patient by minimizing the harm and costs associated with polypharmacy, and minimizing the withdrawal effects of stopping one or more drugs.

Medications that may be considered for discontinuation include drugs that are no longer indicated, drugs that pose a risk for untoward side effects, drugs that interact adversely, drugs that are given to mitigate the side effects of another drug, and addictive drugs that have withdrawal side effects. However, addictive drugs should never be discontinued abruptly, since the withdrawal side effects can be severe.

For more information about how to safely withdraw from these harmful and addictive psychiatric drugs, download and read the booklet Coming Off Psych Drugs Harm Reduction Guide.

Patients For Life

A leading cause of death in patients diagnosed with a serious mental condition (such as schizophrenia, bipolar disorder, and depression) has been preventable medical conditions such as cardiovascular disease (CVD) and diabetes, metabolic disorders which are typical side effects of being treated with second generation (atypical) antipsychotics.

The majority of those who screen positive for these types of metabolic disorders do not receive treatment for these medical conditions. Even worse, the majority of patients being treated with these antipsychotics are not even screened, with simple blood tests, for these side effects.

A tremendous amount of effort, lasting over at least the last 15 years, has been expended in trying to change the U.S. medical system to implement simple blood test screening protocols for patients being prescribed antipsychotics. Many reasons have been given for this reluctance to change, but the most obvious reasons were not among them — the fact that no one knows how these drugs work, that they are addictive, harmful, and are causing side effects that produce continuing income from these patients for life, a life albeit shortened by the metabolic disorders caused by the drugs.

The general attitude of the mental health care industry is that mental disorders are comorbid with metabolic disorders. This means that there is a simultaneous presence of these two chronic conditions in a patient, with little thought given to the fact that metabolic disorders can be the side effect of the drugs being given for the mental disorder. Since the drugs are addictive, harmful, and have nasty side effects, the obvious solution is to stop prescribing the drugs and use one or more of the many non-drug alternatives. This, however, would deprive the industry of one of its top money-makers.

Patients already presenting with CVD or diabetes, or who have known risk factors for these, should not even be considered as candidates for antipsychotics, and should also be screened for any other undiagnosed and untreated medical conditions which may be causing mental symptoms.

A case could be made for malpractice if blood test screening for metabolic disorders is not being performed for patients vulnerable to these diseases, especially since the medications that psychiatrists prescribe increase vulnerability to metabolic syndrome. [Metabolic syndrome is a cluster of metabolic disorders, usually including increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels — that occur together, increasing the risk of heart disease, stroke and diabetes.]

Psychiatrists should be responsible for monitoring any potential side effects associated with the drugs that they prescribe; therefore, it is negligent if monitoring is not being done.

We are seeing a huge increase in the rate of antipsychotic prescriptions among younger pediatric patients, yet the younger one is, the lower one’s chances of being monitored.

Based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), statistics are touted about near “epidemic” rates of mental illness in order to demand more government funds and sell more harmful drugs, making people “patients for life” as the drug adverse events then require more drugs to handle these harmful side effects.

Contact your local, state and federal authorities and legislators and demand that funding for psychiatric promises be revoked until the mental health industry can prove its effectiveness with actual cures.

Mental Health “Care” Coming to Your Community

News articles extolling “Community Mental Health” continue to be published across the United States and abroad. We thought you should know more about this.

These articles generally discuss funding, either the lack or availability of public funding, for various mental health care programs — such as Community Mental Health Centers (CMHC), police Crisis Intervention Teams, Suicide Programs, Veterans Programs, Mental Health Courts, Emergency Management or Crisis Counseling, Violence Prevention, School Safety, or other public/private ventures in the mental health care industry. They also generally complain about the lack of a sufficient number of psychiatrists or psychologists in relation to the target population. Let us help put the record straight about this.

History of CMHC

In 1955, a five-year inquiry by the U.S. Joint Commission on Mental Illness and Health recommended replacing psychiatric institutions with Community Mental Health Centers (CMHCs). According to Henry A. Foley, Ph.D., and Steven S. Sharfstein, M.D., authors of Madness in Government, “Psychiatrists gave the impression to elected officials that cures were the rule, not the exception,” a claim that the psychiatric industry could not and still cannot substantiate.

The advent of Community Mental Health psychiatric programs in the 1960s would not have been possible without the development and use of neuroleptic drugs, also known as antipsychotics, for mentally disturbed individuals. Neuroleptic is from Greek, meaning “nerve seizing”, reflective of how the drugs act like a chemical lobotomy.

These community facilities and programs were promoted as the solution to all institutional problems. The premise, based almost entirely on the development and use of neuroleptic drugs, was that patients could now be successfully released back into society as long as they were taking these drugs. Ongoing service would be provided through government-funded units called Community Mental Health Centers (CMHC). These centers would tend to the patients from within the community, dispensing the neuroleptics that would keep them under control. Governments would save money and individuals would improve faster. The plan was called “deinstitutionalization.”

The first generation of neuroleptics, now commonly referred to as “typical antipsychotics” or “typicals,” appeared during the 1960s. They were heavily promoted as “miracle” drugs that made it “possible for most of the mentally ill to be successfully and quickly treated in their own communities and returned to a useful place in society.”

These claims were false, as neuroleptics are now known to have devastating side effects. In an article in the American Journal of Bioethics in 2003, Vera Sharav stated, “The reality was that the therapies damaged the brain’s frontal lobes, which is the distinguishing feature of the human brain. The neuroleptic drugs used since the 1950s ‘worked’ by hindering normal brain function: they dimmed psychosis, but produced pathology often worse than the condition for which they have been prescribed — much like physical lobotomy which psychotropic drugs replaced.”

Author Peter Schrag wrote in Mind Control, by the mid-seventies enough neuroleptic drugs and antidepressants “were being prescribed outside hospitals to keep some three to four million people medicated fulltime – roughly ten times the number who, according to the [psychiatrists’] own arguments, are so crazy that they would have to be locked up in hospitals if there were no drugs.”

After a decade of the Community Mental Health program, consumer advocate Ralph Nader called it a “highly touted but failing social innovation.” It “already bears the familiar pattern of past mental health promises that were initiated amid great moral fervor, raised false hopes of imminent solutions and wound up only recapitulating the problems they were to solve.”

As for the funding of CMHCs and psychiatric outpatient clinics, the fact is that psychiatry’s budget in the United States soared from $143 million in 1969 to over $9 billion in 1997 – a more than 6,000% increase in funding, while increasing by only 10 times the number of people receiving services. The estimated costs today are over $11 billion.

If collecting these billions in inflated fees for non-workable treatments wasn’t bad enough, in 1990 a congressional committee issued a report estimating that Community Mental Health Centers (CMHCs) had diverted between $40 million and $100 million to improper uses, and that a quarter of all CMHCs had so thoroughly failed to meet their obligations as to be legally subject to immediate recovery of federal funds.

Psychiatrists have consistently blamed the failure of deinstitutionalization on a lack of community mental health funding. In reality, they create the drug-induced crisis themselves and then, shamelessly, demand yet more money.

The CMHCs became legalized drug dealerships that not only supplied drugs to former mental hospital patients, but also supplied psychiatric prescriptions to individuals not suffering from “serious mental problems.” Deinstitutionalization failed and society has been struggling with the resultant homelessness and other disastrous results ever since.

Accompanying the psychiatric push for expanded community mental health programs is their demand for greater powers to involuntarily commit individuals. Psychiatrists disingenuously argue that involuntary commitment is an act of kindness, that it is cruel to leave the disturbed in a tormented state. However, such claims are based on the dual premises that 1) psychiatrists have helpful and workable treatments to begin with, and 2) psychiatrists have some expertise in diagnosing and predicting dangerousness. Both suppositions are patently false.

In spite of receiving huge increases in funding in the United States, psychiatry and psychology not only failed but managed to make things drastically worse; rates of drug abuse, suicide, illiteracy and crime continue to rise.

The real message is this: in spite of an investment of billions of dollars for psychiatric promises, the world has received nothing but presumptuous demands from psychiatric vested interests for more money.

Contact your local, state and federal authorities and legislators and demand that funding for psychiatric promises be revoked until the mental health industry can prove its effectiveness with actual cures.