Archive for February, 2016

Another Day Another Anti-depressant (Again)

Thursday, February 25th, 2016

Another Day Another Anti-depressant (Again)

On July 10, 2015, the U.S. Food and Drug Administration approved Rexulti (brexpiprazole, an atypical antipsychotic) tablets to treat adults with so-called schizophrenia and as an add-on treatment to an antidepressant medication to treat adults with so-called major depressive disorder. We are now starting to see the TV ads for this.

Rexulti is manufactured by Tokyo-based Otsuka Pharmaceutical Company Ltd. and its partner Lundbeck. It might be marketed as a replacement for Abilify (aripiprazole), although clinical trials for its usage to treat ADHD were discontinued, likely due to lack of efficacy. It is still a new drug that has not been tested over a long-term in a real-world population.

Rexulti and other such drugs have a Boxed Warning alerting health care professionals about an increased risk of death associated with the off-label use of these drugs to treat behavioral problems in older people with dementia-related psychosis.

The Boxed Warning also alerts health care professionals and patients to an increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants.

It has the same pattern of debilitating side effects as any other antidepressant or antipsychotic, including addiction and suicidal thoughts and actions. The most common side effects reported by participants taking Rexulti in clinical trials included weight gain and an inner sense of restlessness (akathisia), such as feeling the need to move.

Rexulti is being touted as producing less akathisia, restlessness, and insomnia than other drugs, but it is important to be skeptical of this marketing due to the fact that clinical trials reported all of these side effects. Like all antipsychotics, Rexulti will likely have severe withdrawal symptoms.

While the way Rexulti works is completely unknown, it affects serotonin, dopamine, and norepinephrine neurotransmitters in the brain; and this effect is called a “serotonin-dopamine activity modulator”. Messing with neurotransmitters in the brain without really understanding how they work is serious business; we don’t recommend it. In any case, we can guarantee that this chemical-in-the-brain-based hypothesis is bogus. Full Informed Consent should be your watchword.

Rexulti was studied in two 6-week clinical trials of 1,054 patients aged 18-65. The patients selected for the studies took another antidepressant for at least 8 weeks. Twenty patients discontinued participation due to adverse reactions.  The incidences of akathisia and restlessness, and some other side effects, increased with increases in dose.

We must recognize that the real problem is that psychiatrists and other medical practitioners fraudulently diagnose life’s problems as an “illness” and stigmatize unwanted behavior as  “diseases.” Psychiatry’s stigmatizing labels, programs and treatments are harmful junk science; their diagnoses of “mental disorders” are a hoax – unscientific, fraudulent and harmful. Taking such damaging drugs as Rexulti prevents people from finding out what is really wrong and fixing that.

CCHR believes that everyone has the right to full informed consent. FIND OUT! FIGHT BACK!

CCHR STL MO Legislative Take Action

Thursday, February 18th, 2016

Legislative Take Action

Periodically we let you know the progress of various proposed legislation making its way through the Missouri General Assembly and suggest ways for you to contribute your viewpoint to your state Representative and state Senator.

This time, we’d like to discuss SJR 38 and HB 1755.
Contact your Missouri state Representative and Senator, and let them know what you think about these. We suggest supporting these two bills.  You can find your Representative and Senator, and their contact information, by entering your 9-digit zip code here.
SJR 38 (Senate Joint Resolution)
Creates a new constitutional provision relating parental rights
Introduced by Senator Kurt Schaefer (R-19). Read the full text here.
This proposed constitutional amendment, if approved by the voters, declares that every parent has a fundamental right to exercise exclusive control over all aspects of their minor children’s lives without governmental interference, including but not limited to, decisions regarding their minor children’s custody, upbringing, education, religious instruction, discipline, physical and mental health care, and place of habitation. This fundamental right does not extend to any action by the parent that threatens clear, immediate, and substantial physical injury to their minor child, nor permit a parent to compel a minor child to have an abortion.
This amendment also declares that every parent has a fundamental right to require government entities to obtain the parent’s explicit permission before soliciting or sharing information obtained from a minor child about the child or the child’s family, unless the information is obtained during a criminal investigation or, if enrolled in public school, the child’s knowledge of academic subjects.
This amendment guarantees that every parent shall have the fundamental right to decide what educational settings in which to place their child.
This amendment lists several circumstances in which government interference with parental rights will be justified, including: (1) when protecting a child from a clear, immediate, and substantial threat of physical injury; (2) when a parent has been found by a court to have knowingly exposed a child to physical neglect, abandonment, reckless endangerment, or sexual or physical abuse; (3) when a parent has been found by a court to be incapacitated or mentally incompetent; (4) when a child has been emancipated by court order in accordance with state statutes; (5) when a court has assumed jurisdiction over a minor child charged with or convicted of violating a criminal statute; and (6) when a court of law has assigned parental rights to one parent or a non-biological parent as a result of mental incompetence, adoption, or marital dissolution.
Finally, this amendment permits any parent whose rights have been adversely affected to challenge the constitutionality of the infringing law, policy, or other government act and seek damages and attorney’s fees.
HB 1755 (House Bill)
Specifies that parental liberty to direct the upbringing, education, and care of his or her children is a fundamental right not subject to infringement without demonstrating a compelling governmental interest
Introduced by Representative Kurt Bahr (R-102). Read the full text here.
This bill specifies that the liberty of a parent to direct the upbringing, education, and care of his or her child is a fundamental right. The State of Missouri and any political subdivision of the state is prohibited from infringing on this right without demonstrating a compelling governmental interest. Any law or policy must be narrowly tailored and by the least restrictive means to achieve the interest. These provisions apply to all laws of the state, whether adopted before or after the enactment of these provisions. Any law adopted after the enactment of these provisions is exempt only if the law explicitly excludes the application by reference to these provisions.
Let us know that you contacted your state legislators and let us know any response you get.